IMA Postdoc Seminar (November 13, 2007)

Speaker: Zhian Wang (IMA)

Title: Models for mesenchymal motion in tissue

Abstract: The interaction between cells and extracelluar matrix (ECM) is highly complex and many biological mechanisms have been identified, which provides significant insights of understanding cell invasion such as wound healing, cancer progression and so on. The cell migration using the two strategies, i.e., contact guidance and remodeling of matrix, is termed mesenchymal motion. The mathematical models of mesenchymal motion were developed by Thomas Hillen (2006) and numerical scheme was investigated by Painter (2007). In my talk, I will present the analytic results in addition to their works and explain the findings in the context of biological applications of cell movement in tissues.