Molecular Biology Mysteries: Knotting and linking in DNA

Tuesday, June 18, 2019 - 11:30am - 12:30pm
Keller 3-180
Kenneth Millett (University of California, Santa Barbara)
The replication of DNA requires the assistance of topology changing enzymes called topoisomerases. Efforts to discover the mechanisms by which various enzymes act on DNA has focused attention on questions for which geometrical and topological considerations provide insights as well as raising new questions. In this first lecture, we will explore the biological context and the mathematics that continues to be employed to resolve these questions.